Drug intelligence / Profile preview

D'Cold

Development stage
Unknown
Lead developer
Reckitt
Modality
Small Molecules
Administration
Oral
01

Overview

D'Cold is a prominent over-the-counter (OTC) brand of multi-symptom cold and flu medication, primarily marketed in India. Originally developed by Paras Pharmaceuticals and acquired by Reckitt Benckiser in 2010, the D'Cold product line includes various formulations such as D'Cold Total and D'Cold Next. These products typically combine an analgesic and antipyretic (paracetamol) with a nasal decongestant (phenylephrine) and either a stimulant (caffeine) or an antihistamine (chlorpheniramine maleate). It is indicated for the symptomatic relief of the common cold, including fever, body aches, headache, and nasal congestion. The brand is a staple in the Indian consumer healthcare market, leveraging a combination of well-established small molecule drugs to address upper respiratory symptoms.

Brand names
D'ColdD'Cold TotalD'Cold Next
02

Targets

ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADRA1A (α1A)HRH1 (Histamine H1 Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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