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**D377 + CKD-331** is a combination therapy currently being evaluated for the treatment of **primary hypercholesterolemia** and **familial hypercholesterolemia**. This drug regimen is investigational and is being studied in a randomized, double-blind, phase 3 clinical trial; patients receive oral administration of the combination daily[1]. Mechanistic details for D377 and CKD-331 are not specified in accessible literature, but the combination is under active evaluation as part of lipid-lowering therapy.
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