Drug intelligence / Profile preview

Dan'e Xiaoliu Granules

Development stage
Unknown
Lead developer
Jiangsu Jichuan Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Dan'e Xiaoliu Granules is a Traditional Chinese Medicine (TCM) formulation developed by Jiangsu Jichuan Pharmaceutical for the treatment of uterine fibroids. It is specifically indicated for patients presenting with the "phlegm and blood stasis" syndrome (痰瘀互结证). The formulation typically contains herbal extracts aimed at promoting blood circulation, resolving stasis, and softening hardness to dissipate masses. Clinical development, including Phase 2 trials such as CTR20132715, has focused on evaluating the safety and efficacy of different dosages in reducing the volume of uterine leiomyomas and improving associated clinical symptoms.

Brand names
Dan'e Xiaoliu Granules
Other names
丹莪消瘤颗粒
02

Targets

VEGFA (Vascular endothelial growth factor A)ER (Estrogen receptor)PR (Progesterone receptor)

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