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Dan'ge Fentong
- Development stage
- Unknown
- Lead developer
- Sichuan Academy of Chinese Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Dan'ge Fentong is a Traditional Chinese Medicine (TCM) formulation developed by the Sichuan Academy of Chinese Medicine Sciences, specifically designed for the treatment of type 2 diabetes mellitus and diabetic peripheral neuropathy (DPN). The preparation is primarily composed of extracts from *Salvia miltiorrhiza* (Danshen) and *Pueraria lobata* (Gegen), with key active constituents including salvianolic acids and puerarin. Its mechanism of action is multi-targeted, focusing on improving blood microcirculation, reducing oxidative stress, and inhibiting the release of pro-inflammatory cytokines such as TNF-alpha and IL-6. By addressing these pathways, Dan'ge Fentong aims to protect peripheral nerve fibers from damage caused by chronic hyperglycemia and improve nerve conduction velocity in diabetic patients.
- Brand names
- Dan'ge Fentong Capsule
- Other names
- Dan'ge Fentong JiaonangDange Fentong
02
Targets
AR (Adrenergic receptors)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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