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dapsone + flutamide + tea tree oil
- Development stage
- Unknown
- Lead developer
- Mansoura University
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
DAP-FLU ME is an investigational topical combination micro-emulsion (o/w type) formulation developed by researchers at Mansoura University for the treatment of mild to moderate acne vulgaris. It contains 5% dapsone, 2.5% flutamide, and 5% tea tree oil. Dapsone provides antibacterial and anti-inflammatory effects, while flutamide acts as a non-steroidal anti-androgen to target sebaceous gland overactivity. Tea tree oil serves as both an antibacterial agent and a component of the micro-emulsion base. This topical approach aims to deliver therapeutic efficacy while minimizing the systemic side effects associated with oral administration of dapsone or flutamide.
- Other names
- DAP/FLU Micro-emulsion
02
Targets
AR (Adrenergic receptors)DHPS (Dihydropteroate synthase)
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