darunavir + cobicistat

Darunavir + cobicistat is a fixed-dose combination antiretroviral medication used in the treatment of human immunodeficiency virus (HIV) infection. It contains two active components: - Darunavir, an HIV protease inhibitor that works by inhibiting the viral protease enzyme, thereby preventing viral replication and reducing the amount of HIV in the blood. - Cobicistat, a pharmacokinetic enhancer (booster) that inhibits cytochrome P450 3A (CYP3A) enzymes. This increases plasma concentrations of darunavir by slowing its metabolism, allowing for more effective antiviral activity. The combination is indicated for use with other antiretroviral agents in adults and children weighing at least 40 kg. While it does not cure HIV or AIDS, it helps control viral load and supports immune function[1][2][4][5][8].

Brand names

PrezcobixRezolsta

Other names

darunavir/cobicistat