Decyl(dimethyl)phosphine oxide

Decyl(dimethyl)phosphine oxide is an organophosphorus compound with the chemical formula C₁₂H₂₇OP. It is an amphiphilic molecule, possessing both hydrophobic and hydrophilic regions, which allows it to function as a non-ionic surfactant. This property makes it useful as a detergent in biochemical research, particularly for protein purification and crystallization processes. Beyond its surfactant properties, the compound exhibits biological activity as an inhibitor in various biochemical pathways. It has been shown to catalyze the oxidative deamination of primary and secondary amines, including neuroactive amines like serotonin, suggesting a potential role in neuropharmacology and drug development targeting neuroactive pathways. It is listed as a pharmaceutical in the ZINC15 database.

Other names

Dimethyldecylphosphine oxidePhosphine oxide, decyldimethyl-Decyldimethylphosphine oxide1-dimethylphosphoryldecaneUNII-BQ0G8CN4H9UNII-BQ-0G8CN4H9UNII-BQ 0G8CN4H9