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DendroAnalgesic (home setting)

Development stage
Preclinical
Lead developer
DendroPharm
Modality
Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
01

Overview

DendroAnalgesic (home setting) is a nanoparticle-based opioid analgesic being developed by DendroPharm for the treatment of chronic severe pain. Utilizing the company's proprietary NanoOpiat technology, the drug consists of an opioid agonist encapsulated within a dendritic nanomaterial. This formulation is designed to target peripheral opioid receptors specifically, preventing the drug from crossing the blood-brain barrier. By restricting activity to the peripheral nervous system, DendroAnalgesic aims to provide potent pain relief without the central nervous system side effects typically associated with opioids, such as respiratory depression, sedation, addiction, and constipation. The candidate is specifically intended for use in a home setting and is currently in the preclinical stage of development.

Other names
DendroAnalgesic (chronic pain)
02

Targets

MOR (Mu opioid receptor)

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