Drug intelligence / Profile preview

desflurane + propofol

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Inhalation, Intravenous
01

Overview

A combination anesthetic approach using desflurane (an inhalational anesthetic) and propofol (an intravenous sedative-hypnotic agent). This combination provides synergistic effects for induction and maintenance of general anesthesia, offering more stable hemodynamics than propofol alone in certain procedures. Both agents act on the central nervous system through different but complementary mechanisms.

Brand names
DiprivanSuprane
Other names
2,6-diisopropylphenolDesflurane, USP
02

Targets

GABRR (GABA-A receptor subunit rho)GLRA1 (Glycine receptor subunit Alpha-1)

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