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desflurane + propofol
- Development stage
- Phase 4
- Lead developer
- Baxter
- Modality
- Small Molecules
- Administration
- Inhalation, Intravenous
01
Overview
A combination anesthetic approach using desflurane (an inhalational anesthetic) and propofol (an intravenous sedative-hypnotic agent). This combination provides synergistic effects for induction and maintenance of general anesthesia, offering more stable hemodynamics than propofol alone in certain procedures. Both agents act on the central nervous system through different but complementary mechanisms.
- Other names
- 2,6-diisopropylphenolDesflurane, USP
02
Targets
GABRR (GABA-A receptor subunit rho)GLRA1 (Glycine receptor subunit Alpha-1)GABA-B (Gamma-aminobutyric acid receptor type B)GRIA1 (AMPA receptor subunit GluA1)KCNA1 (Voltage-gated potassium channel subfamily A member 1)SCN2A (Voltage-gated sodium channel protein type 2 subunit alpha)SCN4A (Voltage-gated sodium channel protein type 4 subunit alpha)
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