Drug intelligence / Profile preview

dexamethasone + pranoprofen + sodium hyaluronate + tobramycin

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

A combination eye drop formulation containing dexamethasone (a corticosteroid), pranoprofen (a non-steroidal anti-inflammatory drug), sodium hyaluronate (a lubricant), and tobramycin (an aminoglycoside antibiotic). This combination is primarily used to treat dry eye disease following cataract surgery (phacoemulsification). The components work synergistically to reduce inflammation, prevent infection, and provide lubrication to the eye surface.

02

Targets

16S rRNA (16S ribosomal RNA)23S rRNA (23S ribosomal RNA)GR (Glucocorticoid receptor)COX

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