dexamethasone + procarbazine

A combination of dexamethasone (a corticosteroid) and procarbazine (an antineoplastic agent) used in various chemotherapy regimens for treating certain types of cancers, particularly Hodgkin's lymphoma and brain tumors. Dexamethasone helps reduce inflammation and immune system activity, and is often included to enhance the effectiveness of other drugs and manage side effects like nausea and vomiting[3][5]. Procarbazine is primarily used in combination with other chemotherapeutic drugs for treating Hodgkin's disease and gliomas[1][2], working by damaging cancer cell DNA[9]. This combination is found in regimens like PCV (procarbazine, lomustine, and vincristine) for brain tumors, where dexamethasone is used as an antiemetic[4], and certain lymphoma treatment protocols including a regimen of "methotrexate, VM-26 (teniposide), procarbazine, and dexamethasone" for refractory lymphoma[8].