Drug intelligence / Profile preview

dexamethasone sodium phosphate + isopropyl alcohol + triamcinolone acetonide + bupivacaine

Development stage
Unknown
Lead developer
IT3 Medical
Modality
Small Molecules
Administration
Topical, Intravenous, Intramuscular, Intraarticular, Intralesional
01

Overview

CORTAREN CORTICOSTEROID/ANTI-INFLAMMATORY SYSTEM is a packaged combination kit containing **dexamethasone sodium phosphate**, **triamcinolone acetonide**, **bupivacaine**, and **isopropyl alcohol** for office-based anti-inflammatory and anesthetic use. The therapeutic components combine two corticosteroids with different solubility and duration characteristics and a long-acting local anesthetic: dexamethasone sodium phosphate is a soluble glucocorticoid receptor agonist with relatively rapid onset, triamcinolone acetonide is a depot glucocorticoid receptor agonist with sustained anti-inflammatory activity, and bupivacaine is a voltage-gated sodium channel blocker that provides local anesthesia and analgesia; isopropyl alcohol serves as a topical antiseptic for site preparation rather than a systemic therapeutic. Publicly visible labeling on DailyMed identifies the product as a kit packaged by IT3 Medical rather than a novel investigational asset, and the labeling largely aggregates the component corticosteroid indications, including systemic inflammatory, allergic, dermatologic, rheumatologic, ophthalmic, hematologic, respiratory, endocrine, and certain local musculoskeletal or intralesional uses.

Brand names
CORTAREN CORTICOSTEROID/ANTI-INFLAMMATORY SYSTEM
Other names
dexamethasone sodium phosphate + isopropyl alcohol + triamcinolone acetonide + bupivacaineCortaren
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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