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dexmedetomidine + remifentanil
- Development stage
- Unknown
- Lead developer
- Orion Pharma
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A combination of dexmedetomidine, a selective α2-adrenoceptor agonist with sedative, analgesic, and anxiolytic properties, and remifentanil, an ultra-short acting opioid. This combination provides effective sedation and analgesia with improved respiratory function compared to traditional sedative combinations. It is used in various procedures including endoscopic retrograde cholangio-pancreatography (ERCP), hysteroscopy, catheter ablation for atrial fibrillation, and awake intubation.
- Other names
- dexmedetomidine-remifentanil protocol
02
Targets
ADRA2A (α2A)MOR (Mu opioid receptor)
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