Drug intelligence / Profile preview

dexpanthenol + sodium hyaluronate

Development stage
Unknown
Lead developer
URSAPHARM Arzneimittel
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Ophthalmic, Intranasal
01

Overview

Dexpanthenol + sodium hyaluronate is a fixed-dose combination of two active ingredients used primarily in topical formulations for ocular and nasal applications. Dexpanthenol (a provitamin of pantothenic acid) acts as a moisturizer, protectant, and wound healing agent by promoting fibroblast proliferation and accelerating re-epithelialization. Sodium hyaluronate (the sodium salt of hyaluronic acid) is a naturally occurring glycosaminoglycan with strong water-binding capacity that forms a protective film on mucosal surfaces or the cornea, providing lubrication, moisture retention, anti-inflammatory effects, and supporting tissue repair. The combination is designed to enhance epithelial healing (notably after corneal injury or surgery), relieve symptoms of dry eyes or nasal dryness/irritation due to environmental factors or disease states such as allergic rhinitis or upper respiratory tract infections. Clinical studies have shown that this combination promotes faster corneal reepithelialization and nerve regeneration compared to monotherapy with sodium hyaluronate[2][3][5].

Brand names
HYLO CAREHysan pflegespray
Other names
dexpanthenol and sodium hyaluronatedexpanthenol/sodium hyaluronate
02

Targets

CD44 (CD44 antigen)

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