Drug intelligence / Profile preview

dextran-40 + ginkgo biloba extract + mecobalamin + yufeng ningxin dripping pills

Development stage
Unknown
Lead developer
The First Hospital of Hebei Medical University
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

This conventional therapy is a multi-component treatment regimen utilized at The First Hospital of Hebei Medical University for the management of sensorineural hearing loss (SNHL) accompanied by vertigo. The protocol integrates both Western pharmacological agents and Traditional Chinese Medicine (TCM). It consists of intravenous **Dextran-40**, a plasma volume expander used to improve microcirculation and reduce blood viscosity; intravenous **Ginkgo Biloba extract**, which provides neuroprotective effects and enhances peripheral blood flow; oral **Mecobalamin**, a vitamin B12 analog that promotes nerve repair and myelination; and oral **Yufeng Ningxin Dripping Pills**, a TCM formulation typically containing *Pueraria lobata* (Gegen) used to dilate blood vessels and improve cardiovascular and cerebral circulation. This combination therapy serves as the standard-of-care control in clinical trials evaluating the efficacy of adjunctive treatments like Gastrodin acupoint injection.

Other names
Conventional therapy for sensorineural hearing loss with vertigo (The First Hospital of Hebei Medical University protocol)
02

Targets

MTR (Methionine synthase)PTAFR (Platelet-activating factor receptor)

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