dextromethorphan + carbinoxamine + brompheniramine

This drug is a combination of three pharmaceuticals: **dextromethorphan**, a cough suppressant (antitussive); **carbinoxamine**, an antihistamine; and **brompheniramine**, another antihistamine. Dextromethorphan acts primarily as a low-affinity uncompetitive NMDA receptor antagonist and sigma-1 receptor agonist, suppressing the cough reflex[1]. Carbinoxamine and brompheniramine compete for histamine H1 receptors, reducing allergy symptoms such as runny nose, sneezing, and itchy or watery eyes[2]. The combination would be expected to provide symptomatic relief for upper respiratory tract conditions, primarily cough and allergy symptoms, by respectively dampening cough reflex and blocking histamine-mediated allergic responses.

Other names

dextromethorphan + carbinoxamine + brompheniramine