Drug intelligence / Profile preview

dextromethorphan + phenylephrine + chlorpheniramine

Development stage
Unknown
Lead developer
Blue Cross Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

TusQ-D is a combination pharmaceutical product developed and marketed by Blue Cross Laboratories, primarily used for the symptomatic relief of dry cough and symptoms associated with the common cold or allergic rhinitis. It contains three active ingredients: dextromethorphan hydrobromide (a cough suppressant), phenylephrine hydrochloride (a nasal decongestant), and chlorpheniramine maleate (an antihistamine). Dextromethorphan acts on the cough center in the brain to elevate the cough threshold. Phenylephrine is a sympathomimetic amine that acts on alpha-adrenergic receptors to cause vasoconstriction in the nasal mucosa, reducing congestion. Chlorpheniramine blocks H1 histamine receptors, alleviating allergic symptoms like sneezing and watery eyes.

Brand names
TusQ-D
Other names
TusQ-D Syrup
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)SIGMAR1 (Sigma non-opioid intracellular receptor 1)ADRA1A (α1A)HRH1 (Histamine H1 Receptor)

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