Drug intelligence / Profile preview

dextrose + potassium chloride + sodium chloride

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous
01

Overview

Dextrose + potassium chloride + sodium chloride is a combination intravenous maintenance solution used to provide a source of water, electrolytes, and calories. It is indicated for patients requiring parenteral administration of potassium and sodium chloride along with minimal carbohydrate calories to prevent ketosis and minimize protein breakdown. This combination is commonly used in perioperative settings and for patients who are fasting or unable to maintain oral intake. The solution helps maintain fluid and electrolyte balance, specifically addressing the needs for sodium and potassium replacement while providing glucose as a metabolic substrate. The tonicity of these solutions can vary from hypotonic to isotonic depending on the specific concentrations of sodium and potassium chloride used.

Brand names
GlucionGlucion 5%
Other names
Potassium Chloride in Dextrose and Sodium Chloride InjectionD-glucose + potassium chloride + sodium chlorideDextrose 5% and ElectrolytesKCL in D5NSKCL in D5 1/2NS
02

Targets

SLC5A1 (Sodium Glucose Cotransporter 1)

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