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Dextrose and Sodium Chloride Injection is a sterile, nonpyrogenic intravenous solution that serves as a source of water, electrolytes, and calories. Initially approved by the U.S. FDA in 1970, it is a staple in clinical practice for fluid and electrolyte replenishment. The dextrose component provides essential carbohydrate calories (approximately 4 kcal/g), while sodium chloride provides sodium and chloride ions to maintain osmotic pressure and acid-base balance. It is available in various concentrations, such as 5% dextrose with 0.2% to 0.9% sodium chloride, and is used in both adult and pediatric populations for conditions requiring hydration, maintenance fluid therapy, and caloric supplementation.
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