Drug intelligence / Profile preview

dextrose monohydrate + potassium chloride + sodium lactate + sodium chloride + calcium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

This drug is a **sterile intravenous crystalloid and carbohydrate combination solution** containing dextrose monohydrate, sodium chloride, sodium lactate, potassium chloride, and calcium chloride. It is marketed as Lactated Ringer's and Dextrose or, in potassium-containing presentations, Potassium Chloride in Lactated Ringer's and Dextrose 5% Injection, and is manufactured by ICU Medical. Pharmacologically, it acts by **expanding and maintaining extracellular fluid volume, replacing essential electrolytes, supplying glucose calories, and providing lactate as a bicarbonate precursor with alkalinizing effect**. It is indicated as a source of water, electrolytes, and calories, and for parenteral replacement of extracellular fluid and electrolyte losses in adults and pediatric patients.

Brand names
Lactated Ringer's and DextrosePotassium Chloride in Lactated Ringer's and Dextrose 5% Injection
Other names
dextrose monohydrate + potassium chloride + sodium lactate + sodium chloride + calciumlactated ringer's and dextrose 5% injectionpotassium chloride in lactated ringer's and dextrose 5% injectiondextrose monohydrate + potassium chloride + sodium lactate + sodium chloride + calcium chloride

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