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DFDBA + atorvastatin

Development stage: Unknown
Modality: Small Molecules
Administration: Surgical Implantation, Periodontal

Overview

DFDBA + atorvastatin is a combination therapy used in periodontal treatment, particularly for intrabony defects. DFDBA (Demineralized Freeze-Dried Bone Allograft) provides an osteoconductive scaffold and acts as a source of osteoinductive factors, containing bone morphogenic proteins (BMPs) that stimulate osteoinduction. Atorvastatin, a statin medication, is used as an adjunct to DFDBA in gel form to potentially enhance periodontal regeneration. This combination aims to improve bone fill and clinical attachment level in periodontal defects.

Other names: atorvastatin gelDFDBA with atorvastatinatorvastatin gel + DFDBA

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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