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DHP2306R1 + DHP2306R2 is an investigational **oral combination therapy** of two small-molecule drugs under development by DAE HWA PHARM. As of September 2025, the combination has completed phase 1 clinical trials to evaluate its safety and pharmacokinetic drug–drug interactions in healthy adults. Both DHP2306R1 and DHP2306R2 have also been studied as single agents in the same trial. The primary indication in trials is **musculoskeletal pain**. The exact molecular targets and mechanisms of action for each component have not been disclosed in public sources. The drugs are administered orally in a crossover regimen in the clinical setting[1][5].
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