Drug intelligence / Profile preview

di'ao xinxuekang

Development stage
Unknown
Lead developer
Chengdu Di'ao Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Di'ao Xinxuekang is a traditional Chinese herbal medicine derived from the dried rhizomes of Dioscorea nipponica Makino. It is primarily used for the prevention and treatment of coronary heart disease and atherosclerotic cardiovascular disease. The active ingredient is a water extract of Dioscorea nipponica rhizome. Mechanistically, Di'ao Xinxuekang exerts lipid-lowering and anti-atherosclerotic effects by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) expression and upregulating low-density lipoprotein cholesterol receptor (LDLR) in the liver, thereby improving cholesterol homeostasis. It may also act synergistically with statins such as atorvastatin to further reduce LDL-C levels via modulation of the SREBP2/PCSK9 pathway[1][4]. In some regions, it is also authorized as a traditional herbal medicinal product for relief of headache and muscular pains or cramps in neck, back, and legs based on traditional use[2].

Brand names
Di'ao XinxuekangDiao Xin Xue KangDi'ao Xinxuekang Jiaonang
Other names
DXXK
02

Targets

LDLR (Low-density lipoprotein receptor)RELA (Nuclear Factor Kappa B Subunit p65)HIF1A (Hypoxia-inducible factor 1-alpha)SREBP-2 / SREBF2 (SREBP-2)

Beyond the preview

Go deeper on di'ao xinxuekang.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on di'ao xinxuekang.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call