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Drug intelligence / Profile preview
diacerein + glucosamine (Systopic Laboratories)
- Development stage
- Unknown
- Lead developer
- Systopic Laboratories
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Osicare Plus is a fixed-dose combination tablet containing diacerein and glucosamine (specifically glucosamine sulfate potassium chloride) developed by Systopic Laboratories for the management of osteoarthritis and bone and joint injuries such as fractures. Diacerein is an anthraquinone derivative that acts as a symptomatic slow-acting drug in osteoarthritis (SYSADOA) by inhibiting interleukin-1 beta (IL-1β) synthesis and signaling, thereby reducing joint inflammation and cartilage degradation. Glucosamine is an amino monosaccharide that serves as an essential precursor for glycosaminoglycan and proteoglycan synthesis, supporting cartilage matrix maintenance and joint lubrication. Together, these components work synergistically to alleviate joint pain, reduce swelling, and improve physical mobility in patients with osteoarthritis.
- Brand names
- Osicare Plus
- Other names
- diacerein + glucosamine sulfatediacerein + glucosamine sulfate potassium chloridediacerein and glucosaminediacerein/glucosamine
02
Targets
MMP12 (Macrophage Metalloelastase)IL1B (Interleukin-1 beta)
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