Drug intelligence / Profile preview

diamorphine + morphine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intramuscular, Subcutaneous, Intravenous
01

Overview

Diamorphine + morphine is a combination of two potent opioid analgesics. Diamorphine (heroin) is a narcotic analgesic that acts as a pro-drug of morphine, while morphine is a strong opioid that directly activates opioid receptors. Both drugs act as agonists at opioid receptors (μ, κ, and δ subtypes) to produce analgesia, sedation, and euphoria. This combination would provide powerful pain relief for severe pain, though it's not commonly prescribed as a specific combination since diamorphine is metabolized to morphine in the body.

Other names
heroin + morphinediacetylmorphine + morphine
02

Targets

MOR (Mu opioid receptor)

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