Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
diazepam + pethidine
- Development stage
- Phase 4
- Lead developer
- North District Hospital
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
diazepam + pethidine is a sedation regimen consisting of a benzodiazepine and an opioid analgesic, frequently employed for moderate sedation during endoscopic procedures such as colonoscopy. In the context of North District Hospital studies, the diazepam component is often administered as Diazemuls, a lipid emulsion formulation designed to reduce injection site pain. Diazepam acts as a positive allosteric modulator of the GABA-A receptor, providing anxiolytic, sedative, and amnestic effects. Pethidine (also known as meperidine) serves as a mu-opioid receptor agonist, providing essential analgesia during the procedure. This combination, often referred to as traditional diazemuls-pethidine sedation (DPS), has been used as a standard-of-care comparator in trials evaluating nurse-administered propofol sedation (NAPS).
- Other names
- diazemuls + pethidinemeperidine + diazepamTraditional Diazemuls-Pethidine Sedation
02
Targets
GABRR (GABA-A receptor subunit rho)KOR (Kappa opioid receptor)MOR (Mu opioid receptor)
Beyond the preview
Go deeper on diazepam + pethidine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on diazepam + pethidine.