diclofenac + capsaicin

Diclofenac + capsaicin is a fixed-dose combination topical therapy used primarily for the treatment of osteoarthritis-related pain and inflammation in the knee. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase-1 and -2 (COX-1/COX-2), enzymes responsible for prostaglandin synthesis involved in pain and inflammation. Capsaicin is an active compound from chili peppers that activates TRPV1 receptors on sensory neurons to reduce sensitivity to pain over time. The combination provides both anti-inflammatory effects (from diclofenac) and desensitization of peripheral nociceptors (from capsaicin). It is available as a prepackaged kit containing both agents for topical application directly to affected joints[1][3][5].

Brand names

DermacinRx Lexitral PharmaPakDiclotral PakDiclofex DC Therapy PackCapsFenac PakDicloheal-60Dicloheal60Dicloheal 60ZiclocinDiclareal

Other names

diclofenac/capsaicin kitcapsaicin and diclofenac topical