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Drug intelligence / Profile preview
diclofenac + linseed oil + menthol + methyl salicylate (Spey Medical)
- Development stage
- Unknown
- Lead developer
- Spey Medical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Pardifen Active is a topical combination gel developed by SPEY for the relief of joint and muscular pain, inflammation, and swelling associated with traumatology, musculoskeletal disorders, and localized forms of soft tissue rheumatism. It contains four active ingredients: diclofenac diethylamine (a non-steroidal anti-inflammatory drug that inhibits prostaglandin synthesis via cyclooxygenase enzymes), linseed oil (which possesses anti-inflammatory properties and enhances skin penetration of diclofenac), methyl salicylate (a topical analgesic and counter-irritant), and menthol (a cooling agent and topical analgesic). Together, these components act synergistically to provide localized pain relief and reduce inflammation at the site of application.
- Brand names
- OmnigelPardifen ActiveVolini
- Other names
- diclofenac + linseed oil + menthol + methyl salicylatediclofenac + linseed oil + methyl salicylate + mentholdiclofenac diethylamine + linseed oil + menthol + methyl salicylatediclofenac diethylamine + linseed oil + methyl salicylate + menthol
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPM8 (Transient receptor potential cation channel subfamily M member 8)
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