diclofenac + menthol + methyl salicylate

This is a **topical analgesic combination** containing diclofenac (a nonsteroidal anti-inflammatory drug, NSAID), menthol (a counterirritant), and methyl salicylate (a counterirritant and salicylate). Diclofenac reduces pain and inflammation by inhibiting cyclooxygenase (COX) enzymes, lowering prostaglandin synthesis. Menthol and methyl salicylate provide rapid cooling and warming sensations, primarily distracting from pain via counterirritant effects and by interfering with pain signal transmission at the skin and superficial nerves. Methyl salicylate is also metabolized locally to salicylic acid, contributing further anti-inflammatory properties. The combination is mainly used for temporary relief of minor aches and pains of muscles and joints, e.g., arthritis, simple backache, strains, sprains, and bruises. It is available as a cream, gel, spray, or patch for adults and children over 12 years[1][4][5].

Brand names

VarophenFenovar

Other names

diclofenac-methyl salicylate-menthol topical