diclofenac + paracetamol (Spey Medical)

Painbelin is an oral fixed-dose combination drug containing the nonsteroidal anti-inflammatory drug (NSAID) diclofenac sodium (50 mg) and the analgesic/antipyretic paracetamol (500 mg). Developed by SPEY, Painbelin is approved for use in traumatology and various pain-related conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout attacks, primary dysmenorrhea, post-traumatic and postsurgical pain, and fever. Diclofenac sodium acts by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), thereby blocking prostaglandin synthesis to reduce pain and inflammation. Paracetamol provides complementary analgesic and antipyretic effects, likely through central cyclooxygenase inhibition and modulation of the endogenous cannabinoid system.

Brand names

Painbelin

Other names

acetaminophen + diclofenacacetaminophen + diclofenac sodiumdiclofenac sodium + paracetamolparacetamol + diclofenacparacetamol + diclofenac sodium