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diclofenac + linseed oil + menthol + methyl salicylate (Anglo-French Drugs & Industries)
- Development stage
- Unknown
- Lead developer
- Anglo-French Drugs & Industries
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Anglogesic Plus is a topical analgesic and anti-inflammatory gel developed by Anglo-French Drugs & Industries. It is formulated as a combination of diclofenac, linseed oil, menthol, and methyl salicylate. Diclofenac and methyl salicylate act as non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing prostaglandin synthesis to alleviate pain and inflammation. Menthol acts as a cooling agent by stimulating TRPM8 receptors, providing a soothing sensation and local anesthetic effect. Linseed oil contributes anti-inflammatory properties and helps soothe skin irritation. Anglogesic Plus is indicated for the rapid relief of pain, swelling, and inflammation associated with musculoskeletal disorders, sprains, strains, and joint stiffness.
- Brand names
- Anglogesic PlusAnglogesic Plus Gel
- Other names
- diclofenac diethylamine + linseed oil + menthol + methyl salicylate
02
Targets
TRPM8 (Transient receptor potential cation channel subfamily M member 8)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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