diclofenac potassium + lidocaine

Diclofenac potassium + lidocaine is a combination medication that pairs two active ingredients with complementary mechanisms of action for pain relief. Diclofenac potassium is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking cyclooxygenase enzymes (COX-1 and COX-2), which reduces the production of prostaglandins responsible for pain and inflammation[4]. Lidocaine is a local anesthetic that numbs nerves by blocking sodium-potassium channels, making them less sensitive to pain signals[3][4]. This combination is used for various pain conditions, including arthritis pain, musculoskeletal pain, and procedural pain. Clinical studies have shown that the combination slightly reduces pain scores during procedures like intrauterine device (IUD) insertion, though the reduction may not always reach clinical significance[1]. The topical formulation allows for local pain relief while potentially reducing systemic side effects compared to oral administration of NSAIDs[3][5].

Brand names

Diclona

Other names

diclofenac and lidocaine topicaldiclofenac / lidocaine gel