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diclofenac sodium + diclofenac potassium
- Development stage
- Unknown
- Lead developer
- Novartis
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Diclofenac sodium + diclofenac potassium is an oral fixed-dose combination of two different salts of the non-steroidal anti-inflammatory drug (NSAID) diclofenac, developed by V.S. Pharma (V.S. International). This specific formulation is designed as a sustained-release (SR) tablet, likely utilizing the different solubility profiles of the sodium and potassium salts to achieve both rapid onset and prolonged therapeutic effect. Diclofenac acts by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the synthesis of prostaglandins that mediate pain, inflammation, and fever. By reducing prostaglandin levels, the drug provides analgesic and antipyretic effects. It is primarily used for the management of various acute and chronic pain conditions and the reduction of fever.
- Other names
- Diclofenac sodium and diclofenac potassium tabletsDiclofenac sodium + diclofenac potassium SR
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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