Drug intelligence / Profile preview

diphenhydramine + ammonium chloride + sodium citrate + menthol (Shanghai Universal Biotech)

Development stage
Unknown
Lead developer
Universal Corporation
Modality
Small Molecules
Administration
Oral
01

Overview

Upacof Expectorant is a combination pharmaceutical product developed by Universal Corporation for the symptomatic relief of cough and respiratory congestion. The formulation contains four active ingredients: diphenhydramine hydrochloride, an antihistamine that provides antitussive effects by acting on the central nervous system and reducing allergic responses; ammonium chloride, an expectorant that increases the volume and decreases the viscosity of secretions in the respiratory tract; sodium citrate, which acts as a mucolytic agent; and menthol, which provides a cooling sensation to soothe the throat. It is primarily indicated for conditions such as the common cold, bronchitis, and other upper respiratory tract infections where cough and congestion are present. The product is approved and widely marketed in Kenya and other East African regions.

Brand names
Upacof ExpectorantUpacof
Other names
Upacof Expectorant
02

Targets

mAChR (Muscarinic acetylcholine receptors)HRH1 (Histamine H1 Receptor)

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