Drug intelligence / Profile preview

diphtheria, tetanus, and acellular pertussis vaccine (Zhifei Green Bamboo)

Development stage
Unknown
Lead developer
Zhifei Biological
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The diphtheria, tetanus, and acellular pertussis (DTaP) vaccine developed by Beijing Zhifei Green Bamboo Biopharmaceutical is an acellular subunit vaccine designed to provide immunity against *Corynebacterium diphtheriae*, *Clostridium tetani*, and *Bordetella pertussis*. This specific formulation is a 'component' vaccine, meaning it contains highly purified antigens—typically including diphtheria toxoid, tetanus toxoid, pertussis toxoid, filamentous hemagglutinin, and pertactin—rather than a mixture of co-purified proteins. By presenting these specific subunits to the immune system, the vaccine stimulates the production of neutralizing antibodies that protect against the toxins and bacterial components responsible for the clinical symptoms of diphtheria, tetanus, and pertussis. This approach aims to maintain high efficacy while minimizing the side effects associated with whole-cell or less refined acellular vaccines.

Other names
DTaPDTaP vaccineacellular subunit DTaP vaccinecomponent DTaP vaccineAcellular Diphtheria, Tetanus and Pertussis Vaccine (Component)
02

Targets

PRN (Pertactin)FHA (Filamentous hemagglutinin)Diphtheria toxin

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