Drug intelligence / Profile preview

diphtheria + tetanus + pertussis + hepatitis b + poliomyelitis vaccine

Development stage
Unknown
Lead developer
Parent
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This entry refers to a combination vaccine developed by Sanofi Pasteur, typically known as a pentavalent or hexavalent vaccine (such as **Hexaxim** or **Hexyon** when including the Haemophilus influenzae type b component), which provides protection against diphtheria, tetanus, pertussis, hepatitis B, and poliomyelitis. In the context of the provided clinical trial data (NCT04024358), this vaccine is used as a concomitant pediatric immunization in studies evaluating Sanofi's investigational quadrivalent meningococcal conjugate vaccine (**MenACYW-TT**; brand name **MenQuadfi**). The trial specifically assesses the safety and immunogenicity of MenACYW-TT when administered alongside this DTaP-HepB-IPV combination in infants and toddlers. The vaccine contains diphtheria and tetanus toxoids, acellular pertussis antigens, recombinant hepatitis B surface antigen, and inactivated poliovirus types 1, 2, and 3.

Brand names
HexaximHexyon
Other names
diphtheria + tetanus + pertussis + hepatitis b + poliomyelitis vaccine-Sanofi Pasteur, a Sanofi Company-meningococcal infectionDTaP-HepB-IPV vaccineDTaP-IPV-HB
02

Targets

Poliovirus capsid proteinsDiphtheria toxinFHA (Filamentous hemagglutinin)HBsAg (Hepatitis B surface antigen)

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