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diphtheria and tetanus toxoids and acellular pertussis + measles, mumps, rubella + varicella virus
- Development stage
- Unknown
- Lead developer
- Merck
- Modality
- Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Live Attenuated Vaccines → Live Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular, Subcutaneous
01
Overview
This is a combination vaccine that provides immunization against six diseases: diphtheria, tetanus (lockjaw), pertussis (whooping cough), measles, mumps, rubella (German measles), and varicella (chickenpox). The formulation includes inactivated bacterial toxoids for diphtheria and tetanus; acellular components of Bordetella pertussis; live attenuated viruses for measles, mumps, rubella; and live attenuated varicella-zoster virus. The mechanism of action involves stimulating the immune system to produce antibodies against each pathogen or toxin component without causing disease. This results in immunity that protects against future infection by these pathogens[5][7][8]. Combination vaccines like this are primarily indicated for routine childhood immunization to prevent outbreaks of these highly contagious diseases.
- Brand names
- ProQuad
- Other names
- MMRV vaccinemeasles, mumps, rubella, varicella vaccineMMRV combination vaccine
02
Targets
Diphtheria toxin
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