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This quadrivalent vaccine is a combination product designed to provide active immunization against diphtheria, tetanus, pertussis, and invasive diseases caused by Haemophilus influenzae type b (Hib). Developed by Yuxi Watson Biotechnology, a subsidiary of Walvax Biotechnology, it was the first domestically developed DTaP-Hib combination vaccine in China. The vaccine consists of diphtheria and tetanus toxoids, acellular pertussis antigens (typically pertussis toxoid and filamentous hemagglutinin), and the Hib capsular polysaccharide (polyribosylribitol phosphate) conjugated to a tetanus toxoid carrier. By combining these four components into a single injection, the vaccine reduces the number of required shots for infants and children, improving compliance and coverage. It works by stimulating the immune system to produce neutralizing antibodies against the respective toxins and pathogens, providing long-term protection against these serious infectious diseases.
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