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diphtheria vaccine + tetanus vaccine + inactivated poliomyelitis vaccine
- Development stage
- Unknown
- Lead developer
- Sanofi
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
This is a **combination vaccine** composed of diphtheria toxoid, tetanus toxoid, and inactivated poliovirus antigens. It is designed to induce an immune response and confer protection against **diphtheria**, **tetanus**, and **poliomyelitis**. The mechanism of action relies on stimulating adaptive immunity, causing the body to produce specific antibodies and cell-mediated responses against the bacterial toxins (diphtheria, tetanus) and the poliovirus. It is commonly administered to children as part of routine immunization schedules and is used worldwide for booster immunization, especially before school entry. The vaccine does not treat active infections; it is purely prophylactic. Approved brand formulations include Kinrix (GlaxoSmithKline), Quadracel (Sanofi), Adacel-Polio (Sanofi), and Boostrix-Polio (GlaxoSmithKline)[1][3][5][6][7].
- Brand names
- KinrixQuadracelAdacel-PolioBoostrix-Polio
- Other names
- DTaP-IPVDTPa-IPVDPT-IPVDTaP/IPVTdap-IPV
02
Targets
Diphtheria toxin
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