Drug intelligence / Profile preview

disease-modifying therapies + taurine

Development stage
Unknown
Lead developer
Sichuan Provincial People's Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

Taurine is being investigated as an adjunctive therapy to standard disease-modifying treatments (DMTs) for the treatment of relapsing-remitting multiple sclerosis (RRMS). Developed by the Sichuan Academy of Medical Sciences, this combination therapy aims to enhance remyelination and neuroprotection. Taurine, a naturally occurring amino acid and endogenous metabolite, is thought to work by reversing metabolic pathway flux and increasing the availability of serine, a critical building block for glycosphingolipids that constitute the myelin sheath. The Phase 2 clinical trial (NCT07263607) evaluates the efficacy of oral taurine supplementation in reducing MRI lesions, decreasing relapse rates, and slowing disability progression in patients already receiving stable DMT therapy.

Other names
DMTs + taurineTaurine Treatment for Multiple Sclerosis

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