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Drug intelligence / Profile preview
DKF-MA201 (octreotide)
- Development stage
- Preclinical
- Lead developer
- Dongkook Pharmaceutical
- Modality
- Peptides
- Administration
- Intramuscular
01
Overview
DKF-MA201 is a long-acting, sustained-release generic formulation of octreotide (specifically octreotide acetate) developed by Dongkook Pharmaceutical. It is designed as a once-monthly intramuscular injection utilizing Dongkook's proprietary microsphere-based drug delivery system (DDS) platform. DKF-MA201 is being developed for the treatment of acromegaly and gastrointestinal/pancreatic neuroendocrine tumors, aiming to provide a generic alternative to Novartis's blockbuster drug Sandostatin LAR. By slowly releasing octreotide over a one-month period, the formulation maintains stable therapeutic blood levels, thereby suppressing the hypersecretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) to improve patient compliance and clinical outcomes.
- Brand names
- Octrin LAROctrin LAR Injection옥트린라르옥트린라르주사
- Other names
- octreotide acetate옥트레오티드옥트레오티드아세트산염
02
Targets
SSTR2 (Somatostatin receptor type 2)SSTR3 (Somatostatin receptor 3)SSTR5 (Somatostatin receptor 5)
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