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docetaxel + mitomycin

Development stage: Unknown
Modality: Small Molecules
Administration: Intravenous

Overview

A combination chemotherapy regimen consisting of docetaxel and mitomycin. Docetaxel is a taxoid antineoplastic agent that binds to microtubules with high affinity, preventing cell division. Mitomycin is an antineoplastic antibiotic that inhibits DNA synthesis through cross-linking DNA strands. The combination has shown synergistic effects in preclinical studies, particularly when combined with capecitabine, as taxanes and mitomycin C can enhance anti-tumor activity through up-regulation of thymidine phosphorylase (TP).

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DNA

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