Drug intelligence / Profile preview

docetaxel + SHR1020

Development stage
Preclinical
Lead developer
Hengrui Pharmaceutical
Modality
Small Molecules
Administration
Intravenous
01

Overview

Docetaxel is a taxane-class antineoplastic agent used in the treatment of various cancers, including breast, lung, prostate, stomach, and head and neck cancers. It works by promoting the assembly of microtubules from tubulin dimers and stabilizing them against depolymerization, thereby inhibiting cell division and leading to cancer cell death. Docetaxel is administered intravenously. SHR1020 is an investigational drug; while specific details about its mechanism are not available in the provided sources, it is being studied in combination with docetaxel for potential synergistic effects in oncology indications.

Other names
None
02

Targets

TUBB (Tubulin (alpha and beta subunits))

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