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DoCo-Pro-RBD-1 + MF59
- Development stage
- Unknown
- Lead developer
- University of Melbourne
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
DoCo-Pro-RBD-1 + MF59 is an experimental protein subunit vaccine developed for the prevention of COVID-19. It consists of a recombinant protein that mimics the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein, specifically targeting the beta variant. The vaccine is adjuvanted with MF59®, an oil-in-water emulsion adjuvant designed to enhance immune response. By presenting a viral RBD antigen similar to that found in SARS-CoV-2, this vaccine stimulates the immune system to produce specific antibodies and activate T cells against the virus, thereby conferring immunity. The primary indication is as a booster dose in adults previously vaccinated with other COVID-19 vaccines[1][2][4].
- Other names
- DoCo-Pro-RBD-1 + M59DoCo-Pro-RBD-1 + MF59®
02
Targets
SARS-CoV-2 spike
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