Drug intelligence / Profile preview

docosahexaenoic acid + minoxidil

Development stage
Preclinical
Lead developer
Samson Clinical
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

This is a **combination drug** consisting of *docosahexaenoic acid* (DHA) and *minoxidil*. **Docosahexaenoic acid** is an omega-3 fatty acid, typically used as a dietary supplement for general health and sometimes included in formulations for skin and hair health. **Minoxidil** is an antihypertensive small molecule drug and peripheral vasodilator, FDA-approved for the treatment of severe hypertension and for topical use in the treatment of androgenetic alopecia (pattern hair loss). Minoxidil’s mechanism involves lengthening the anagen (growth) phase of the hair cycle and increasing blood flow to hair follicles, promoting hair growth[1][2][3][4]. The rationale for combining DHA and minoxidil would be to harness potential synergistic effects on hair and scalp health, though no specific branded or standardized pharmaceutical product containing both agents appears in current regulatory databases or literature.

02

Targets

PPAR (PPAR family)AHR (Aryl hydrocarbon receptor)KATP channel (ATP-sensitive potassium channel)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)MAPK3 (Mitogen-activated protein kinase 1)

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