Drug intelligence / Profile preview

docusate sodium + sorbitol

Development stage
Phase 4
Lead developer
Ferring Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

**Docusate sodium + sorbitol** is a fixed-dose rectal laxative combination used for short-term relief of rectal constipation and bowel evacuation before selected examinations or procedures. Docusate sodium is an anionic surfactant stool softener that promotes water penetration into dry fecal material, while sorbitol provides local osmotic and lubricating effects that increase stool water content and facilitate evacuation. It is supplied as a rectal solution or enema, with bowel evacuation commonly occurring within approximately 5 to 20 minutes.

Brand names
Dokusatnatrium/Sorbitol EvolanKlyx
Other names
docusate + sorbitoldocusate sodium and sorbitoldocusate sodium/sorbitoldokusatnatrium/sorbitol
02

Targets

Colonic luminal water content and osmotic environment

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