Drug intelligence / Profile preview

donepezil + galantamine + rivastigmine

Development stage
Unknown
Lead developer
Eisai
Modality
Small Molecules
Administration
Oral, Transdermal
01

Overview

This represents a combination of three separate acetylcholinesterase inhibitors (donepezil, galantamine, and rivastigmine) that are used in the treatment of Alzheimer's disease. Each drug works by inhibiting acetylcholinesterase to increase acetylcholine levels in the brain, which may improve cognitive function in patients with dementia. These medications are typically prescribed individually rather than as a fixed-dose combination.

Brand names
AriceptExelonRazadyneReminyl
Other names
Cholinesterase InhibitorsAChEIsAcetylcholinesterase inhibitors
02

Targets

ButyrylcholinesteraseAcetylcholinesteraseNicotinic Acetylcholine Receptor

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