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Drug intelligence / Profile preview
doxylamine + pyridoxine + folic acid
- Development stage
- Unknown
- Lead developer
- Dwd Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Goodmorn** is a combination pharmaceutical product marketed by **Dwd Pharmaceuticals** in India, primarily indicated for the management of **nausea and vomiting of pregnancy (NVP)**, commonly known as morning sickness. The formulation typically consists of three active ingredients: **doxylamine succinate**, a first-generation antihistamine that acts as an H1 receptor antagonist with antiemetic properties; **pyridoxine hydrochloride** (Vitamin B6), which is involved in amino acid metabolism and has been shown to reduce nausea; and **folic acid** (Vitamin B9), which is essential for fetal neural tube development. This combination provides a multi-modal approach to managing pregnancy-related nausea while ensuring essential vitamin supplementation during the first trimester.
- Brand names
- Goodmorn
- Other names
- doxylamine succinate + pyridoxine hydrochloride + folic acid
02
Targets
FOLR1 (FRα)FOLR2 (Folate receptor beta)HRH1 (Histamine H1 Receptor)mAChR (Muscarinic acetylcholine receptors)
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