Drug intelligence / Profile preview

Duracain + fentanyl + ropivacaine

Development stage
Unknown
Lead developer
Janssen Pharmaceutica
Modality
Small Molecules
Administration
Epidural, Intrathecal
01

Overview

Based on the search results, a specific product or standard combination named "Duracain + fentanyl + ropivacaine" was not found. The search results primarily discuss combinations of ropivacaine with fentanyl, and bupivacaine with fentanyl, particularly for epidural analgesia in labor and post-operative pain. Information regarding the queried combination is therefore limited, and it is treated as likely an incorrect or non-standard term for a clinical mix. Information below pertains largely to the Ropivacaine + Fentanyl combination as discussed in the search results: Ropivacaine + fentanyl is a combination used for epidural analgesia, especially in labor pain management and post-operative pain control. This combination is noted for providing effective pain relief with a lower incidence of motor blockade compared to bupivacaine-fentanyl combinations. Ropivacaine is an amide local anesthetic with lower lipophilic characteristics, associated with reduced potential for motor blockade and neurotoxicity. Fentanyl is an opioid analgesic that enhances the analgesic effect of ropivacaine.

02

Targets

NaV (Voltage-gated sodium channels)MOR (Mu opioid receptor)

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