Duration of eradication regimen-Incheon St.Mary's Hospital-Helicobacter pylori infection

Duration of eradication regimen-Incheon St.Mary's Hospital-Helicobacter pylori infection refers to a specific clinical treatment protocol evaluated in the K-CREATE study (NCT04713306) for the eradication of *Helicobacter pylori*. This protocol utilizes a tailored approach where the choice and duration of therapy are guided by clarithromycin resistance patterns identified via dual priming oligonucleotide-polymerase chain reaction (DPO-PCR). Patients with susceptible strains are treated with triple therapy (typically a combination of a proton pump inhibitor, amoxicillin, and clarithromycin) for either 7 or 14 days. Patients with resistant strains receive bismuth quadruple therapy (typically a combination of a proton pump inhibitor, bismuth subcitrate, metronidazole, and tetracycline) for either 7 or 14 days. The study aims to determine the optimal treatment duration to maximize eradication rates in the context of increasing regional antibiotic resistance.

Other names

Tailored H. pylori Eradication TherapyDuration of eradication regimen